Similarly, we asked whether the absence or presence of somatic mutations in NOTCH1 (Supplementary Table S5), SYNE1 (Supplementary Table S6), PKHD1 (Supplementary Table S7), and EP400 (Supplementary Table S8) in BCC tissue was associated with a difference in magnitude of the differential expression of genes. The gene discussed is SYNE1; the disease is skin basal cell carcinoma.