Particular types of malignancies are associated with systemic secretion of PTHrP, for example, tumors like cell carcinomas of the lung, head and neck, esophagus, skin, or cervix, carcinomas of the breast, kidney, prostate, and bladder cancer of the ovary and non-Hodgkin lymphoma [3,16]. The gene discussed is PTHLH; the disease is non-Hodgkin lymphoma.