Also, for vascular quantification, or cellular or hypoxic heterogeneity from immunohistochemistry data, the tumours were stained with haematoxylin and eosin (HE = measured cellular density), anti-CD31 (measured vessel area), anti-Ki67 (measured proliferating cellular density) or anti-pimonidazoles (measured hypoxia). Here, MKI67 is linked to neoplasm.