KCNJ5 and atrial fibrillation: Genetic variations in the inward rectifier potassium channels (Kir3.4 and K2P3.1), both specific atrial channels, along with the dysregulation of cardiac ion channels, including Ito, IKur, ICa,L, ISK, IK1, IKACh, and IK2P, are crucial to the electrophysiological remodeling associated with AF [7].