Figure 2G displays representative western blots of the expression of β-catenin. A significant decrease in expression of this protein is observed in HCC rats compared to NT group, while the HCC/PFD group did not present significant changes (Figure 2H). On the other hand, in Figure 2I, it is observed that in the nuclear fraction, there is an increase in β-catenin and c-Myc in the HCC group; however, treatment with PFD significantly reduced the expression of both proteins in the cell nucleus (Figure 2J,K). This evidence concerns the gene MYC and hepatocellular carcinoma.