The expression levels of IL-2 (P ═ 0.010), IL-4 (P ═ 0.028), IL-10 (P ═ 0.011), IL-12p70 (P ═ 0.034), IL-17 (P ═ 0.024), tumor necrosis factor (TNF)-α (P ═ 0.003), and interferon (IFN)-γ (P ═ 0.007) were related to lymph node metastasis. The gene discussed is IL4; the disease is metastatic malignant neoplasm in the lymph nodes.