We then examined the expression of various autophagy-related genes, including MITF, TFEB, TFE3, SQSTM1, ULK1, ULK2, ATG3, ATG7, ATG9A, ATG9B, ATG12, ATG13, ATG14, MAP1LC3A, LAMP1, ATP6V1H, and ATP6V1C, in TCGA-HNSCC samples with high HIF1A-AS2 levels compared with those with low HIF1A-AS2 levels (Supplementary Fig. S5C) or HIF1A-AS2-overexpressing HNSCC cells compared with control cells (Supplementary Fig. S5D). Here, SQSTM1 is linked to head and neck squamous cell carcinoma.