NOTCH1 and breast cancer: MiR-34a inhibited the migration, invasion, and proliferation (Avtanski et al., 2016) and modulated drug sensitivity (Kastl et al., 2012; Li et al., 2012) in breast cancer cells by affecting antiapoptotic genes Bcl-2 and CCND1 (Avtanski et al., 2016) and the Ras family proteins, NOTCH1 and PRKD1 (Li et al., 2012).