Chronic Kidney Disease (CKD), characterized by a reduced glomerular filtration rate [eGFR < 60 mL/min/1.73 m2) or the presence of albuminuria (urine albumin-creatinine ratio (UACR) ≥ 30 mg/g], represents a significant and escalating global health concern (1). The gene discussed is ALB; the disease is chronic kidney disease.