The high ApoA-I group had significantly higher survival rates compared to the low ApoA-I group at the same time points, indicating a significant association between ApoA-I levels and PFS and OS in patients with CRC (PFS: 64.8% vs. 45.2%, P < 0.001; OS: 66.1% vs. 48.6%, P < 0.001) (Figure 1). The gene discussed is APOA1; the disease is colorectal carcinoma.