FA other study has indicated that 10-methylenetetrahydrofolate reductase (MTHFR) is a candidate gene involved in the process of arteriosclerosis, and MTHFR is an enzyme that catalyzes the reduction of 5, 10-methyltetrahydrofolate to 5-MTHF (8). The gene discussed is MTHFR; the disease is arteriosclerosis.