The Neu-2 cluster expressed more genes associated with ribosomal processes and translation initiation, such as Rpl26 and Rps8. Notably, genes that were related to migration and chemotaxis were predominantly expressed in Neu-3, Neu-4, Neu-5 and Neu-6 clusters (Fig. 1f), suggesting that the motility of blood neutrophils in AD mice was affected. This evidence concerns the gene NEU4 and Alzheimer disease.