Subsequently, we utilized the GSE68779 dataset to analyze the infiltration of m7G-related immune cell clusters in the NPC TME, as shown in Fig. 2A. Notably, the infiltrated levels of CD4+ T_C2, B_C3, and Mac_C3 in tumor samples were significantly higher than that in normal samples (Fig. 2B). This evidence concerns the gene CD4 and nasopharyngeal carcinoma.