FCGR3A and lymphoma: When the Fc region of the antibody is bound to an Fc receptor on the NK cell’s surface (e.g., FcγRIII, a.k.a. CD16a, referred to as CD16 hereafter) and the Fab region is bound to a target specific antigen (e.g., CD20), the target lymphoma B cell (in this example) is lysed.