IDH1 and central nervous system cancer: In order to reveal the relationship between IDH1 mutation, tumour grade and PTBP1 expression, TCGA LGG sample cohort, CGGA mRNA_325, CGGA mRNA_301, CGGA mRNA_693 sample cohort were used to compare the difference in PTBP1 expression between IDH1 mutant and wild type, and different tumour grades of glioma patients with PTBP1 expression in patients.