To demonstrate more rigorously the relationship between PTBP1 and glioma prognosis, we constructed uni-cox and multi-cox regression models and generated nomograms by considering the factors of PTBP1 expression, age, gender, tumour WHO grade, IDH1 mutation, and 1p19q codeletion as variables affecting glioma prognosis. The gene discussed is PTBP1; the disease is central nervous system cancer.