TG and amyotrophic lateral sclerosis: Within the top 10 most abundant pathways identified, naphthalene degradation, retinol metabolism penicillin and cephalosporin biosynthesis were upregulated in FMD group, while tryptophan metabolism, benzoate degradation, Foxo signaling pathway, longevity regulating pathway, biosynthesis of siderophore group nonibosomal peptides, amyotrophic lateral sclerosis (ALS) and thyroid hormone synthesis were downregulated in FMD group (Fig. 3g).