NFKB1 and infection: The Western-blot analysis conducted on inflammatory pathways, namely NF-κB and MAPKs, revealed that Aim2−/− mice kidneys exhibited significantly lower levels of activation of p-IκB/IκB, p-ERK/ERK, p-JNK/JNK, and p-p38/p38 in comparison to their WT counterparts following infection (Fig. 2M–Q).