The transcriptional activity of FOXM1 is tightly regulated and suppressed by p53 tumor suppressor protein, and p53 mutations detected in about 80% of TNBC patients lead to upregulation of FOXM1 and uncontrolled cell proliferation, migration, invasion, drug resistance, tumor growth, and progression in breast and other cancers [11, 12]. Here, FOXM1 is linked to neoplasm.