TIM-3, Gal-9, and CEACAM1 expression levels were increased on CD8+ Tc at days 17 and 24 in mice injected with FLT3-ITD MLL-PTD AML cells and undergoing allo-HCT with allogeneic Tc transfer compared with untreated control mice (Supplemental Figure 1D). This evidence concerns the gene FLT3 and acute myeloid leukemia.