LRIG1 and hydrops fetalis: While the bioinformatic analysis comparison of Lrig1+ and CD34+ HF KSC populations yielded a total of 3,802 DEGs (Figure 1G), in contrast, there were a total of 276 DEGs (P < 0.05) from the analysis of HPV8-CERtg versus WT HF KSC populations (Figure 2A).