As a result, IA-0130 most effectively inhibited the proliferation of HEK-Blue IL-6 cells, and surface plasmon resonance analysis confirmed that IA-0130 specifically binds to gp130, not IL-6 or IL-6Rα, and IA-0130 inhibits ovarian cancer cell proliferation, migration, invasion, and tumor growth [26]. The gene discussed is IL6; the disease is neoplasm.