Among these genes, MTOR (Burchert et al. 2005), STAT3, MCL1 (Bewry et al. 2008), LAMC1 (Zhang et al. 2022), and KRAS (Agarwal et al. 2007) have been reported to play roles in imatinib resistance in chronic myeloid leukemia in parallel with our findings. The gene discussed is LAMC1; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.