Genotype distributions of the MIF gene rs1049829 and rs755622 variants were in accordance with Hardy–Weinberg equilibrium (p > 0.05) as demonstrated in Tables 3, 4 Interestingly, a significant association between the T allele of rs1049829 variant of MIF gene and the protective effect against BC (OR = 0.51, 95% CI = 0.34–0.77, p = 0.001). The gene discussed is MIF; the disease is breast cancer.