SMOC1 and Parkinson disease: The study intentionally omits an in-depthexploration of structural aspects of αS–membrane binding.Instead, it is focused on the core binding energetics, offering afoundational understanding of MαS/OαS–lipid interactions.Future investigations taking into account the complexities of cellularenvironments and additional molecular factors would offer a more comprehensiveview of the roles of MαS and OαS in PD.