Additionally, a recent publication found that ASPSCR1::TFE3 and VCP (also known as p97), an ATPase that can modulate protein membrane and complex interactions, directly interact in the genetic ASPS mouse model and patient cell lines (Pozner et al., 2024; Meyer and Weihl, 2014). The gene discussed is ASPSCR1; the disease is alveolar soft part sarcoma.