In contrast, the overexpression of the Endoplasmic reticulum protein 29 (ERP29) gene, CD69 molecule (CD69), protein tyrosine phosphatase non-receptor type 22 (PTPN22) gene, Cytochrome B-245 beta chain (CYBβ) gene, and complement C4B gene is positively correlated with the risk of T1DM (OR values all > 1). This evidence concerns the gene PTPN22 and type 1 diabetes mellitus.