Analysis of contributor genes to these ICs (Fig. 4e) revealed that SRY-box transcription factor 4 (SOX4) is expressed exclusively in patient 9 by all cancer cells, but sample 9_1 is characterized notably by the expression of calmodulin 2 (CALM2) whereas sample 9_2 cancer cells are enriched in secretory leukocyte peptidase inhibitor (SLPI) and N-myc downstream regulated 1 (NDRG1). The gene discussed is CALM2; the disease is cancer.