CD8A and psoriasis: Therefore, we selected the five subpopulations that were specifically upregulated in psoriatic lesions for further analysis and defined them as the psoriasis-specific CD8+ T cell subpopulation (IS CD8+ T cells), and defined the other CD8+ T cell subpopulations as the non-psoriasis-specific CD8+ T cell subpopulation (Other CD8+ T cells).