In contrast, the Department of Endocrinology of the Ninth People’s Hospital of Shanghai Jiao Tong University School of Medicine published another study of 46, XY DSD patients in 2018 (Wang et al., 2018); patients with classical complete AIS (CAIS) were excluded, and AR mutations remained in the top three in this cohort (Wang et al., 2018). Here, AR is linked to disorder of sexual differentiation.