For cardioprotection, pre-treating, healing cardiac tissue, and hypertension-related issues oxytocin also shows positive and promising results in WKY, SHR, Sprague Dawley (SD), and W rats after either exercise-related or exogenous oxytocin adage (Martins et al., 2005; Moghimian et al., 2012; Gutkowska et al., 2016; Wang et al., 2020). The gene discussed is OXT; the disease is hypertensive disorder.