CD274 and lung adenocarcinoma: To further investigate its potential in therapy response prediction, [18F]F-BMS-986192 was evaluated in vitro, by flow cytometry and Western blotting, and in vivo, by PET imaging of xenograft mice models bearing using human tumors with varying PD-L1 expression levels (lung mucoepidermoid carcinoma H292, lung adenocarcinoma H358, and ovarian clear cell carcinoma ES2 cell lines) (159).