In a specific example genomic information relating to Hypotrichosis 8 was screened by PVP, initially variant rs766783183 present in the gene KRT25 was ranked at 172 (without the inclusion of model organism data); when this data was included this variant’s prioritisation ranking significantly improved to rank 8, this variant was ultimately the confirmed molecular diagnosis for Hypotrichosis 8 [32]. This evidence concerns the gene KRT25 and hypotrichosis.