Similarly, in our study utilizing KEGG gene sets, we found that oxidative phosphorylation, citrate cycle (TCA cycle), Alzheimer’s disease, and selenoamino acid metabolism were inhibited in the high expression groups of RHBDF2 (Figure 2F) and TNFRSF10B (Figure 2G). Here, TNFRSF10B is linked to early-onset autosomal dominant Alzheimer disease.