Several molecular biomarkers have been considered as prognostic factors for NPC, including, EBV mRNA-interfering complementary RNAs (micRNAs), Epstein-Barr virus (EBV) DNA load, vascular endothelial growth factor (VEGF), cyclooxygenase-2 (COX-2), and epidermal growth factor receptor (EGFR) overexpression (Pan et al., 2013; Li et al., 2023; Zhang et al., 2015). Here, PTGS2 is linked to nasopharyngeal carcinoma.