In doing so, mutability of GLP-1R and neighboring genes might differ depending on species as measured by two factors associated with high mutation rates in human chromosomes: (i) proximity to telomeres, and (ii) high adenine and thymine (A + T) content, since full blown spectrum of cognitive decline as seen in humans with AD is reported to be different in the said primate or Chimpanzees (Sherwood et al., 2011; Lacreuse et al., 2020). The gene discussed is GLP1R; the disease is Mental deterioration.