Cardiac apoptosis-associated piRNA (HAAPIR) promotes cardiomyocyte apoptosis by recruiting N-acetyltransferase 10 (NAT10) to facilitate the acetylation of TFEC mRNA and thus is a key regulator of apoptosis in cardiomyocyte cells in response to ischemia and reperfusion injury [46]. This evidence concerns the gene NAT10 and ischemia.