Additionally, receptors and ligands associated with epithelial cells and having a p < 0.05 include TIMP1_FGFR2 between CAF (Cancer-Associated Fibroblast) and Epithelial cells, FGFR2_CD83 between Epithelial and Macrophage cells, C5AR1_RPS19, CD74_APP, CD74_COPA, and CD74_MIF between Macrophage and Epithelial cells, and CD74_MIF between T cells and Epithelial cells. This evidence concerns the gene APP and cancer.