IKBIP and neoplasm: To further verify whether IKBIP promotes ESCC development in vivo, we constructed tumor cell-derived xenograft models (NC, sh-1, Vector and OE) by subcutaneously injecting 1 × 106 KYSE-150 cells transfected with pLV-NC, pLV-IKBIP-sh1, pCDH-Vector or pCDH-IKBIP into the right axilla of nude mice.