CAT and ischemic stroke: However, the activity of this receptor is commonly linked with the anti-degenerative and anti-inflammation effect, which was presented inter alia by Inestrosa et al. in rat hippocampal neurons (abolishment of the Aβ effect after Pparγ activation) or increased neuronal death in Pparγ-knock-out mouse primary neurons after ischemic stroke, which was also correlated with a decrease in CAT and SOD protein expression [47].