HHLA2 and neoplasm: Multivariate analysis revealed that high CCL17-T maintained its prognostic significance for predicting both RFS [HR 1.407 (1.117–1.771), P = 0.004] and OS [HR 1.633 (1.274–2.095), P < 0.001], along with tumor size, MVI, differentiation, CD34, Treg/CD8, CCR4-T, CCL17-I, HHLA-2-T, CD73-T, and CCR4 + CD73 + cells for OS, and age, tumor size, MVI, Treg/CD8, CCR4-T, CCL17-I, HHLA-2-T, CD73-T, and CCR4 + CD73 + cells for RFS (Table 4).