GGCT and neoplasm: Reports indicate significant accumulation of GGCT in various cancers, such as breast, gastric cancer, ovarian cancer and other cancers.(Gromov et al. 2010; Zhang et al. 2016; Li et al. 2018; Taniguchi et al. 2018) Numerous studies have indicated high expression of GGCT in tumor tissues, yet the underlying biological mechanisms of GGCT overexpression in tumor tissues remain unclear.