By ranking the degree values (Fig. 2), it can be seen that ALB (degree = 70), IL6 (degree = 66), TNF (degree = 66), AKT1 (degree = 64), CASP3 (degree = 58), and SRC (degree = 56) interacted more frequently, indicating that these six targets play a stronger role in the treatment of cryptosporidiosis with oxymatrine. This evidence concerns the gene CASP3 and cryptosporidiosis.