In patients with obesity, we also observed an increased risk of death for patients in CRP-Q4 (CRP-Q4, HRadj: 1.40 [95% CI = 0.64–3.09]) compared with CRP-Q1, however, the precision of the estimate was weaker than in the other BMI groups. Here, CRP is linked to obesity due to melanocortin 4 receptor deficiency.