Aside from cancer, histone acetyltransferases are implicated in neurodevelopmental disorders such as TAF1/TAFII250/KAT4 mutations in autism spectrum disorder (ASD) (Gudmundsson et al. 2019), MYST3/KAT6A mutations in Arboleda-Tham syndrome (ARTHS) (Tham et al. 2015), and HRNPA2B1 loss-of-function mutations in amyotrophic lateral sclerosis (ALS) (Fig. 4; Kim et al. 2022). The gene discussed is TAF1; the disease is amyotrophic lateral sclerosis.