For example, a study in breast cancer cells demonstrated that MeCP2 binds to the promoter regions of ribosomal protein L11 (RPL11) and ribosomal protein L5 (RPL5) genes and reduces their expression, which then promotes a ubiquitin-mediated p53 degradation pathway promoting breast cancer cell growth (Tong et al. 2020). The gene discussed is TP53; the disease is breast cancer.