SMARCB1 and neoplasm: One of the first documented implications of remodelers in cancer was the identification of BAF as a tumor suppressor in rare malignant rhaboid tumor (MRT) caused by biallelic inactivation of BAF47 (hSNF5, INI1, and SMARCB1) (Versteege et al. 1998; Kadoch and Crabtree 2015).