We used Spearman (upper right) and Pearson (lower left) correlation analysis to study the relationship between Mitophagy-Related Genes (MRGs) in the TCGA-HNSCC dataset, identifying significant associations between RPS27A and TOMM22, TOMM7, UBA52 (Supplementary Figure 1B). This evidence concerns the gene TOMM22 and head and neck squamous cell carcinoma.