IGF1 and obesity due to melanocortin 4 receptor deficiency: Patients with permanent GHD were also classified according to AACE cutoff for GST based on BMI range for healthy weight (<25 kg/m2), overweight (≥25 kg/m2 and <30 kg/m2), and obesity (≥30 kg/m2) (Table 7) and IGF-1 SDS levels.