GH1 and hypophysitis: Interestingly, patients with hypothalamic-pituitary disease and 1 to 2 or ≥3 pituitary defects showed an optimal GH cutoff value of 1.0 (92% sensitivity, 100% specificity) or 2.0 μg/L (96% sensitivity, 100% specificity) depending on the administration of a fixed (1 or 1.5 mg >90 kg body weight) or weight-adjusted glucagon injected dose (0.03 mg/kg, maximum 3 mg), respectively (57).