Important genes like the autoimmune regulator (AIRE) gene and four of the six interferon receptor subunits (which act as receptors for both type III interferon (IFN) ligands and cytokines interleukin-10, interleukin-22 and interleukin-26) are found on this chromosome, leading to an unbalanced gene dosage in individuals with DS [7]. Here, IFNAR2 is linked to Dravet syndrome.