As demonstrated in Figure 3R and Supplemental Tables 4 and 5, further correlation analyses showed a positive/negative correlation between the structural parameters of white matter (LFB, MBP, SMI32, SMI32/MBP ratio, and Caspr/Nav1.6) and neurobehavioral outcomes (sensorimotor and cognitive functions) in all experimental mice; this indicated that posttrauma white matter structural injury or loss in mouse brains was highly associated with sensorimotor and cognitive impairments. This evidence concerns the gene SCN8A and Cognitive impairment.