MGAT5 and neoplasm: These included (i) the creation of neoantigens, potentially via the addition of new sugar moieties to (normally) unmodified mannose moieties; (ii) uncloaking of existing antigens whose processing and presentation are blocked via steric hindrance in Mgat5-WT cells; and (iii) changes in tumor cell glycosylation resulting an enhanced ability of T cells to recognize and/or kill target cells.