To determine the overall impact of VGLL1 expression on the transcriptomic profiles of the different cancer cells, global RNA-seq data from PANC10.05, BT20, and Bewo cells treated with siScramble versus siVGLL1 was analyzed without prior filtering on the genes shown to bind VGLL1 by ChIP-seq. The gene discussed is VGLL1; the disease is cancer.